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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal <t> dose-response algorithm. </t>
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TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal dose-response algorithm.

Journal: Scientific Reports

Article Title: Expression of the BAD pathway is a marker of triple-negative status and poor outcome

doi: 10.1038/s41598-019-53695-0

Figure Lengend Snippet: TNBC and non-TNBC cell cisplatin IC 50 values in the presence and absence of the BAD pathway kinase inhibitors perifosine and H89. Drug IC 50 values were computed using GraphPad with Sigmoidal dose-response algorithm.

Article Snippet: Comparing cisplatin IC 50 values in the presence and absence of perifosine or H89, which were calculated using the sigmoidal dose-response algorithm (as implemented in GraphPad Prism 7), indicated that the potentiation of cisplatin by a BAD protein kinase inhibitor was significant in the majority of TNBC cells but not in non-TNBC cells (Table ).

Techniques: